Regulation of Type I Interferon Signaling in Latently HIV-Infected CD4+ T lymphocytes

潜伏感染 HIV 的 CD4 T 淋巴细胞中 I 型干扰素信号传导的调节

• 批准号: 331328
• 负责人: Sandstrom Teslin S
• 金额: $ 1.27万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-12-01 至 2015-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=331328&lang=en
• 关键词: Aids; Cd4+ T Lymphocyte; Hiv; Immunology; Interferon; Latency; Maraba; Oncolytic; Vesiculer Stomatitis Virus; Virology

Since their introduction almost thirty years ago, HIV-specific antiretroviral drugs have largely decreased AIDS related deaths. However, adverse side effects of these treatments have been described, including accelerated aging and neurological dysfunction

艾滋病毒特异性抗逆转录病毒药物自近30年前推出以来，已大大减少了与艾滋病有关的死亡。然而，这些治疗的不良副作用已经被描述，包括加速衰老和神经功能障碍