Transduction of wild type mice with AAV2-alpha-synuclein-GFP drives expression of alpha-synuclein in the brain stem region that controls muscle atonia during REM sleep.
Transduction of wild type mice with AAV2-alpha-synuclein-GFP drives expression of alpha-synuclein in the brain stem region that controls muscle atonia during REM sleep.
用 AAV2-α-突触核蛋白-GFP 转导野生型小鼠可驱动脑干区域中 α-突触核蛋白的表达，从而控制快速眼动睡眠期间的肌肉无力。
批准号：
324334
负责人：
McKenna Dillon
金额：
$0.06万
依托单位：
依托单位国家：
加拿大
项目类别：
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-01-01 至 2016-01-01
中文摘要
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英文摘要
Rapid eye movement (REM) sleep is the stage of sleep during which dreaming occurs and the body is paralyzed. Control of this paralysis relies on an area of the brain stem called the subcoeruleus (SubC). When the SubC stops functioning, paralysis is lost a
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