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Contribution of pathoadaptive mutations to antibiotic resistance development in chronic lung infections of Pseudomonas aeruginosa

Contribution of pathoadaptive mutations to antibiotic resistance development in chronic lung infections of Pseudomonas aeruginosa
铜绿假单胞菌慢性肺部感染中病理适应性突变对抗生素耐药性发展的贡献
批准号：
320290
负责人：
Poole Keith R
金额：
$51.27万
依托单位：
Queen's University (Kingston, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-03-01 至 2020-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=320290&lang=en
关键词：
Antibiotic Resistance Chronic Infection Mutation Pseudomonas Aeruginosa Stress Response

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Pseudomonas aeruginosa is a bacterium that causes severe, long-term (i.e. chronic) and often lethal infections in humans with chronic lung disease. The organism is innately resistant to many antibiotics and often develops what might be termed high-level a
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Environmental influences on multidrug efflux gene expression and antibiotic resistance in P. aeruginosa
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