Advanced endoscopy imaging technology

先进的内窥镜成像技术

• 批准号: 481739-2015
• 负责人: Fang, Qiyin
• 金额: $ 1.82万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=582062
• 关键词: Advanced; endoscopy; imaging; technology

During gastrointestinal (GI) endoscopy, it is critical to localize lesions for effective diagnosis and treatment. For example, it is important to document the location and extent of colorectal cancer lesions and/or inflammatory, potentially pre-neoplastic diseases (e.g. Crohns disease, ulcerative colitis). Without accurate, reproducible lesion localization, it is difficult to confirm complete lesion removal, assess treatment effect, or detect lesion recurrence during follow-up surveillance tests. On the other hand, the colon is contractile and mobile within the abdomen, localization of lesions with an endoscope is very imprecise. We plan to develop an endoscope tracking technology combined with 3D reconstruction of colon side wall through a panoramic imaging endoscope to produce a map of the entire colonic mucosa side wall such that mucosal lesions can be referenced and located in subsequent surgical or colonoscopy procedures.

在胃肠道内窥镜检查中，定位病变是有效诊断和治疗的关键。例如，重要的是记录结直肠癌病变和/或炎性、潜在的肿瘤前疾病（例如克罗恩病、溃疡性结肠炎）的位置和程度。如果没有准确的、可重复的病灶定位，就很难在随访监测试验中确认病灶完全切除、评估治疗效果或检测病灶复发。另一方面，结肠是可收缩的并且在腹部内是移动的，用内窥镜定位病变是非常不精确的。 我们计划开发一种内窥镜跟踪技术，通过全景成像内窥镜结合结肠侧壁的3D重建，以产生整个结肠粘膜侧壁的地图，以便在随后的手术或结肠镜检查过程中可以参考和定位粘膜病变。