Inflammatory activation in the juvenile rat hippocampus mediates altered plasticity underlying cognitive impairment, anxiety, and depression after repeat mild traumatic brain injury

重复轻度创伤性脑损伤后，幼年大鼠海马体的炎症激活介导了认知障碍、焦虑和抑郁的可塑性改变

• 批准号: 348028
• 负责人: Meconi Alicia L
• 金额: $ 7.65万
• 依托单位: University of Victoria (British Columbia)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-10-01 至 2018-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=348028&lang=en
• 关键词: Anxiety And Depression; Behavioural Neuroscience; Cell Death And Neurodegeneration; Confocal Microscopy; Immunohistochemistry; In Vivo Electrophysiology; Inflammation; Juvenile Mild Traumatic Brain Injury; Learning And Memory; Repeat Mild Traumatic Brain

Concussions are an important problem facing Canadian healthcare. They are caused by a rapid change in head movement, like striking an object, and produce a variety of symptoms like learning and memory problems, increased anxiety, and depression. Concussio

脑震荡是加拿大医疗保健面临的一个重要问题。它们是由头部运动的快速变化引起的，比如撞击物体，并产生各种症状，如学习和记忆问题，焦虑增加和抑郁。孔库西奥