Nanoparticle formulations for DNA-targeted radiotherapy and imaging: combinations with chromatin-modifying compounds

用于 DNA 靶向放射治疗和成像的纳米颗粒制剂：与染色质修饰化合物的组合

• 批准号: FT120100942
• 负责人: Dr Tom Karagiannis
• 金额: $ 51.77万
• 依托单位: Baker IDI Heart and Diabetes Institute
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT120100942
• 关键词: Nanoparticle; formulations; DNA; targeted; radiotherapy

This project will develop a new approach for treating and imaging cancer using nanoparticles which target specific cells for cancer therapy and diagnostic imaging. The nanoparticles will be combined with compounds that alter the architecture of DNA to make therapy more effective and to improve the safety of imaging.

该项目将开发一种使用纳米颗粒治疗癌症和成像的新方法，该纳米颗粒针对癌症治疗和诊断成像的特定细胞。纳米粒子将与改变DNA结构的化合物结合，以使治疗更有效，并提高成像的安全性。