Fermentability of selected pentose-rich hydrolysates to high value products by Native pentose-fermenting yeasts

综合谷物加工合作社（IGPC）是一家总部位于安大略的农民所有合作社，成立于1999年。 2002年在安大略的艾尔默建立一个乙醇工厂，为当地生产商的玉米增值。乙醇工厂 2008年成功开始运营。凭借领先的技术和经验丰富的管理，IGPC 公司迅速成为加拿大乙醇行业的主要参与者之一。IGPC生产超过 180，000，000升乙醇，150，000吨动物饲料，以及用于可再生燃料生产的玉米油。IGPC是 有兴趣使其基材和产品范围多样化。最近，它一直在探索 从玉米秸秆和其它木质纤维素产生的水解产物生产更高价值的产品 生物质。水解产物通过专有的预处理方法产生并分离成流 含有C6糖的物流和含有高比例的戊糖（C5）糖的物流（基于干物质）。而 在工业中充分证明了富含葡萄糖的流的使用，C5流的有效转化为价值 需要添加产物以提高工艺的经济性，从而实现长期的商业可行性。在这 根据申请人的建议，申请人建议与IGPC启动一项合作研究项目，以测试发酵能力 通过选择的戊糖发酵酵母将IGPC水解产物转化为乙醇或木糖醇。成功 这项研究的进行将产生有关IGPC水解产物的相对毒性的信息，以及 因为它们适合用作发酵生产燃料和化学品的底物。

Integrated Grain Processors Co-operative (IGPC) is an Ontario based farmer owned co-operative founded in 2002 to build an ethanol plant in Aylmer, Ontario to add value to local producers' corn. The ethanol plant successfully began operations in 2008. With leading edge technology and experienced management, IGPC has quickly established itself as one of the leading players in the Canadian Ethanol Industry. IGPC produces over 180,000,000 L of ethanol, 150,000 T of animal feed, as well as corn oil for renewable fuel production. IGPC is interested in diversifying its substrate and product range. Recently, it has been exploring the possibility of producing higher value products from hydrolysates generated from corn stover and other lignocellulosic biomass. The hydrolysates were produced by a proprietary pretreatment method and separated into a stream containing C6 sugars and a stream containing a high ratio of pentose (C5) sugars on a dry matter basis. While use of glucose rich streams is well demonstrated in the industry, efficient conversion of the C5 stream to value added products is required to improve the process economics for long term commercial viability. In this proposal, the applicant proposes to initiate a collaborative research project with IGPC to test the fermentability of the IGPC hydrolysates by selected pentose-fermenting yeasts to produce ethanol or xylitol. Successful undertaking of this research will yield information about the relative toxicity of the IGPC hydrolysates, as well as their suitability to serve as substrates for fermentative production of fuel(s) and chemical(s).