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Profound sex differences in a sub-strain of Sprague-Dawley rats exhibiting genetically determined hyper-responsiveness to VEGFR2 inhibition causing severe pulmonary arterial hypertension

Profound sex differences in a sub-strain of Sprague-Dawley rats exhibiting genetically determined hyper-responsiveness to VEGFR2 inhibition causing severe pulmonary arterial hypertension
Sprague-Dawley 大鼠亚种中存在显着的性别差异,表现出基因决定的对 VEGFR2 抑制的高反应性,导致严重的肺动脉高压
批准号:
339911
负责人:
Stewart Duncan J
金额:
$10.14万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-11-01 至 2017-11-01

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中文摘要
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英文摘要
Pulmonary arterial hypertension (PAH) is a disease of narrowing or loss of lung blood vessels causing high blood pressure in the lungs and the right side of the heart. This leads to enlargement of the right side of the heart, heart failure and ultimately
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Imbalance Between Vascular Injury and Repair in PAH
  • 批准号:
    469687
  • 项目类别:
    Operating Grants
  • 资助金额:
    $63.25万
  • 财政年份:
    2022
  • 负责人:
    Stewart Duncan J
  • 依托单位:
Microvascular Endothelial Loss and Regeneration in Acute Lung Injury
  • 批准号:
    462755
  • 项目类别:
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  • 资助金额:
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  • 财政年份:
    2022
  • 负责人:
    Stewart Duncan J
  • 依托单位:
COVID-19 Variant Supplement - Cellular Immuno-Therapy for COVID-19 Induced Acute Respiratory Distress Syndrome: the CIRCA-19 Trial
  • 批准号:
    443293
  • 项目类别:
    Operating Grants
  • 资助金额:
    $3.64万
  • 财政年份:
    2021
  • 负责人:
    Stewart Duncan J
  • 依托单位:
Cellular Immuno-Therapy for COVID-19 Induced Acute Respiratory Distress Syndrome: the CIRCA-19 Trial
  • 批准号:
    429558
  • 项目类别:
    Operating Grants
  • 资助金额:
    $135.54万
  • 财政年份:
    2020
  • 负责人:
    Stewart Duncan J
  • 依托单位:
海外基金