Cellular and molecular mechanisms of epithelial ion transport and excretion in invertebrates

无脊椎动物上皮离子转运和排泄的细胞和分子机制

• 批准号: RGPIN-2015-05359
• 负责人: ODonnell, Michael
• 金额: $ 5.17万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=590379
• 关键词: Cellular; molecular; mechanisms; epithelial; ion

All terrestrial animals regulate the concentrations of ions in their cells and body fluids. In addition, they must eliminate wastes and toxins from their bodies. This research examines how transporting epithelia within insects and nematode worms excrete toxins and regulate the levels of water, ions, acids and bases. Some of our experiments on epithelial transport use model organisms, such as fruit flies and the nematode worm

所有陆生动物都能调节细胞和体液中的离子浓度。此外，他们还必须清除体内的废物和毒素。本研究探讨了昆虫和线虫体内的运输上皮如何排泄毒素并调节水、离子、酸和碱的水平。我们的一些上皮运输实验使用模式生物，如果蝇和线虫