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The roles of the CaVbeta2 subunit and the synaptic protein interaction site in determining Ca2+ channel function in neuroendocrine secretion

The roles of the CaVbeta2 subunit and the synaptic protein interaction site in determining Ca2+ channel function in neuroendocrine secretion
CaVbeta2亚基和突触蛋白相互作用位点在神经内分泌分泌中Ca2通道功能中的作用
批准号：
RGPIN-2015-05536
负责人：
Fisher, Thomas
金额：
$2.19万
依托单位：
University of Saskatchewan
依托单位国家：
加拿大
项目类别：
Discovery Grants Program - Individual
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-01-01 至 2016-12-31
来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=590491
关键词：
rolesCaVbeta2subunitsynapticprotein

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英文摘要
The flow of Ca2+ into neurons through voltage-gated Ca2+ (CaV) channels triggers the release of neurotransmitters and hormones and the intracellular targeting of these channels is therefore of fundamental importance for intercellular communication. CaV channels are composed of a CaValpha1 subunit and one of four CaVbeta subunits, which may help transport channels to axon terminals. The two types of Ca2+ channels most important in synaptic release (CaV2.1 and CaV2.2) contain a peptide sequence that allows them to interact with synaptic proteins and is thus called the “synprint” site.
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The role of the Ca2+-dependent phospholipase C delta1 isoform in neuronal osmosensitivity
  • 批准号：
    RGPIN-2020-06334
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $2.33万
  • 财政年份：
    2022
  • 负责人：
    Fisher, Thomas
  • 依托单位：
    University of Saskatchewan
The role of the Ca2+-dependent phospholipase C delta1 isoform in neuronal osmosensitivity
  • 批准号：
    RGPIN-2020-06334
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $2.33万
  • 财政年份：
    2021
  • 负责人：
    Fisher, Thomas
  • 依托单位：
    University of Saskatchewan
The role of the Ca2+-dependent phospholipase C delta1 isoform in neuronal osmosensitivity
  • 批准号：
    RGPIN-2020-06334
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $2.33万
  • 财政年份：
    2020
  • 负责人：
    Fisher, Thomas
  • 依托单位：
    University of Saskatchewan
The roles of the CaVbeta2 subunit and the synaptic protein interaction site in determining Ca2+ channel function in neuroendocrine secretion
  • 批准号：
    RGPIN-2015-05536
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $2.19万
  • 财政年份：
    2019
  • 负责人：
    Fisher, Thomas
  • 依托单位：
    University of Saskatchewan
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