Kindling, behavior, and hippocampal plasticity

点燃、行为和海马可塑性

• 批准号: 222912-2011
• 负责人: Kalynchuk, Lisa
• 金额: $ 2.91万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=594039
• 关键词: Kindling; behavior; hippocampal; plasticity

The general purpose of our research is to study brain plasticity--the remarkable ability of the brain to change with experience. Brain plasticity is what makes each one of us unique. It provides a substrate for the positive emotions of love and attachment, for learning and remembering, and for understanding the world around us. However, brain plasticity is a double-edged sword: Under certain circumstances, the constant re-shaping of brain activity can also promote abnormal excitation or inhibition of brain cells, altered emotion and personality, and lost memories. This aberrant form of brain plasticity is the focus of my research.

我们研究的总体目的是研究大脑的可塑性--大脑随着经验而变化的非凡能力。大脑的可塑性使我们每个人都独一无二。它为爱和依恋的积极情绪提供了基础，为学习和记忆以及理解我们周围的世界提供了基础。然而，大脑可塑性是一把双刃剑：在某些情况下，大脑活动的不断重塑也会促进脑细胞的异常兴奋或抑制，改变情绪和个性，失去记忆。这种大脑可塑性的异常形式是我研究的重点。