Catalytic Methods and Cascade Processes in Organic Synthesis

有机合成中的催化方法和级联过程

• 批准号: 249822-2013
• 负责人: West, Frederick
• 金额: $ 6.12万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=594347
• 关键词: Catalytic; Methods; Cascade; Processes; Organic

We wish to invent and apply new, strategy-level transformations in synthesis, using of novel reactive intermediates and their unique bond-formation reactivity. Successful implementation of this research will unveil new ways to build the complex structures found in many bioactive natural products. Importantly, this work will also generate new knowledge about the reactivity of these intermediates by examining their behaviour in complex molecular frameworks.

我们希望在合成中发明和应用新的战略级转化，使用新的活性中间体及其独特的成键反应性。这项研究的成功实施将揭示构建许多生物活性天然产品中发现的复杂结构的新方法。重要的是，这项工作还将通过检查这些中间体在复杂分子框架中的行为来产生关于它们的反应性的新知识。