Development of New Stereoselective Routes to Fluorinated Butyrolactones

氟化丁内酯立体选择性新路线的开发

• 批准号: 484687-2015
• 负责人: West, Frederick
• 金额: $ 1.82万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=584479
• 关键词: Development; New; Stereoselective; Routes; Fluorinated

A fluorine-containing carbohydrate, 2-deoxy-2-fluoro-2-methylribonolactone, is a valuable building block for the synthesis of several important antiviral compounds. The Company, TC Scientific, wishes to develop an efficient and cost-effective synthetic route to this target. The West group will explore several complementary strategies for the chemical synthesis of this compound, and the most promising one will be developed for scale-up at the company. If successful, this project will add several important products to the Company's catalog.

一种含氟碳水化合物，2-脱氧-2-氟-2-甲基核糖内酯，是一种有价值的结构单元， 几种重要的抗病毒化合物的合成。TC Scientific公司希望开发一种 高效和成本效益的合成路线。西方集团将探索几个互补的 该化合物的化学合成策略，最有前途的一个将被开发用于 公司的规模扩大。如果成功的话，这个项目将为公司增加几个重要的产品。 catalog.