Computational inference and analysis of ancestral genomes

祖先基因组的计算推理和分析

• 批准号: 262081-2013
• 负责人: Blanchette, Mathieu
• 金额: $ 5.03万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=594720
• 关键词: Computational; inference; analysis; ancestral; genomes

Advances in DNA sequencing technologies have resulted in the sequencing of the genomes of a large number of species from all domains of life. This represents an incredible opportunity to study the evolution of these genomes and interpret patterns of evolutionary events to help identifying functional elements in genomes. This also opens the door to the intriguing possibility that the genomes of ancestral species maybe be computationally inferred from those of extant species.

DNA测序技术的进步已经导致对来自所有生命领域的大量物种的基因组进行测序。这代表了一个令人难以置信的机会来研究这些基因组的进化并解释进化事件的模式，以帮助识别基因组中的功能元件。这也为一个有趣的可能性打开了大门，即祖先物种的基因组可能是从现存物种的基因组中计算出来的。