Understanding and exploiting lysine polyphosphorylation as a new post-translational modification regulating cell growth

理解和利用赖氨酸多磷酸化作为调节细胞生长的新翻译后修饰

• 批准号: 344660
• 负责人: Downey Michael S
• 金额: $ 53.47万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-03-01 至 2021-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=344660&lang=en
• 关键词: Cell Growth; Function Genomics; Metabolism; Model Systems Of Human Disease; Phosphatase; Polyphosphorylation; Post-Translational Modification; Protien-Protein Interactions; Ubiquitin; Yeast

Background: Essential processes in our cells are controlled by molecules called proteins, which are comprised of individual building blocks called amino acids. These can be modified by chemicals in the cell in different ways that tell a protein what to do

背景： 我们细胞中的基本过程是由称为蛋白质的分子控制的，蛋白质由称为氨基酸的单个构建块组成。这些可以被细胞中的化学物质以不同的方式修改，告诉蛋白质该做什么