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Characterization of a gene regulatory pathway involving proteins mutated in SMA, ALS, and FTD

Characterization of a gene regulatory pathway involving proteins mutated in SMA, ALS, and FTD
涉及 SMA、ALS 和 FTD 突变蛋白的基因调控途径的表征
批准号:
347078
负责人:
Greenblatt Jack F
金额:
$55.69万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-03-01 至 2020-03-01

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中文摘要
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英文摘要
Mutations in SMN cause spinal muscular atrophy (SMA), a fatal neurodegenerative disease of infancy. Mutations in many proteins (e.g. senataxin, FUS, and TDP-43) can cause the fatal adult neurodegenerative diseases amyotrophic lateral sclerosis (also know
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Mechanisms of gene regulation by the human C2H2 zinc finger proteins and interacting RNAs
  • 批准号:
    347035
  • 项目类别:
    Operating Grants
  • 资助金额:
    $77.14万
  • 财政年份:
    2016
  • 负责人:
    Greenblatt Jack F
  • 依托单位:
Human gene expression regulatory mechanisms
  • 批准号:
    354473
  • 项目类别:
    Operating Grants
  • 资助金额:
    $447.0万
  • 财政年份:
    2016
  • 负责人:
    Greenblatt Jack F
  • 依托单位:
Elucidation of protein interaction networks for the human transcription factors
  • 批准号:
    252011
  • 项目类别:
    Operating Grants
  • 资助金额:
    $112.5万
  • 财政年份:
    2012
  • 负责人:
    Greenblatt Jack F
  • 依托单位:
Roles of human RNA polymerase II CTD-interacting proteins in the regulation of gene expression
  • 批准号:
    238230
  • 项目类别:
    Operating Grants
  • 资助金额:
    $55.65万
  • 财政年份:
    2011
  • 负责人:
    Greenblatt Jack F
  • 依托单位:
海外基金