Characterization of a gene regulatory pathway involving proteins mutated in SMA, ALS, and FTD
Characterization of a gene regulatory pathway involving proteins mutated in SMA, ALS, and FTD
批准号:
347078
负责人:
Greenblatt Jack F
金额:
$55.69万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-03-01 至 2020-03-01
中文摘要
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英文摘要
Mutations in SMN cause spinal muscular atrophy (SMA), a fatal neurodegenerative disease of infancy. Mutations in many proteins (e.g. senataxin, FUS, and TDP-43) can cause the fatal adult neurodegenerative diseases amyotrophic lateral sclerosis (also know
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