课题基金 / 基金详情

The pathogenesis of CHCHD10 in familial ALS

The pathogenesis of CHCHD10 in familial ALS
CHCHD10在家族性ALS中的发病机制
批准号：
346450
负责人：
Shoubridge Eric A
金额：
$27.29万
依托单位：
Montreal Neurological Institute-Hospital
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-03-01 至 2019-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=346450&lang=en
关键词：
Amyotrophic Lateral Sclerosis Coiled Helix Coiled Helix Proteins Frontotemporal Dementia Ips Cells Mitochondrial Disease Motor Neurons Myopathy Oxidative Phosphorylation Spinal Muscular Atrophy

项目摘要

项目成果

Shoubridge Eric A的其他基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Mitochondrial dysfunction has been implicated in some familial forms of ALS, but the evidence for mitochondrial involvement has not been compelling. In the last two years mutations in CHCHD10, which codes for a bona fide mitochondrial protein, have been r
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Role of the mitochondrial carrier family protein SLC25A46 in mitochondrial dynamics and early onset neurodegenerative diseases
Functional analysis of mitochondrial-endoplasmic reticulum contact sites
Molecular pathology of SLC25A46, a degenerate mitochondrial carrier protein causing early onset neurodegenerative disease
Posttranscriptional regulation of mitochondrial gene expression