Molecular pathology of SLC25A46, a degenerate mitochondrial carrier protein causing early onset neurodegenerative disease

SLC25A46（一种导致早发性神经退行性疾病的简并线粒体载体蛋白）的分子病理学

• 批准号: 346445
• 负责人: Shoubridge Eric A
• 金额: $ 28.68万
• 依托单位: Montreal Neurological Institute-Hospital
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-03-01 至 2019-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=346445&lang=en
• 关键词: Cell Cycle Regulation; Cellular Senescence; Lipid Transfer; Membrane Biogenesis; Mitochondrial Cristae Architecture; Mitochondrial Disease; Mitochondrial Er Contacts; Mitochondrial Metabolite Carrier

All cells in the body require a steady source of chemical energy to carry out their normal physiological functions. The majority of this chemical energy, which is packaged as a compound called ATP, is produced by the oxidation of carbohydrate and fat in a

体内的所有细胞都需要稳定的化学能源来执行其正常的生理功能。这种化学能的大部分以称为 ATP 的化合物的形式包装，是通过碳水化合物和脂肪在体内的氧化产生的。