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Novel CAR-T cell therapy targeting a Wilms Tumor 1 peptide presented by multiple HLA-DP alleles

Novel CAR-T cell therapy targeting a Wilms Tumor 1 peptide presented by multiple HLA-DP alleles
针对由多个 HLA-DP 等位基因呈递的肾母细胞瘤 1 肽的新型 CAR-T 细胞疗法
批准号:
342733
负责人:
Hirano Naoto
金额:
$50.12万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-03-01 至 2021-03-01
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中文摘要
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英文摘要
Recent clinical trials have convincingly demonstrated that immunotherapy with anti-CD19 chimeric antigen receptor (CAR) T cells can induce impressive clinical responses in children and adult patients with refractory B cell acute lymphocytic leukemia. Mos
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Development of bi-specific T cell engagers (BiTEs) for the treatment of acute myeloid leukemia (AML)
  • 批准号:
    478239
  • 项目类别:
    Operating Grants
  • 资助金额:
    $74.12万
  • 财政年份:
    2023
  • 负责人:
    Hirano Naoto
  • 依托单位:
Development of TCR-engineered T cells against novel NY-ESO-1 epitopes for the treatment of triple negative breast cancer
  • 批准号:
    435378
  • 项目类别:
    Operating Grants
  • 资助金额:
    $104.77万
  • 财政年份:
    2020
  • 负责人:
    Hirano Naoto
  • 依托单位:
Development of a novel mesothelin CAR-T immunotherapy and pharmacologic combinations for triple negative breast cancer
  • 批准号:
    390724
  • 项目类别:
    Operating Grants
  • 资助金额:
    $92.79万
  • 财政年份:
    2018
  • 负责人:
    Hirano Naoto
  • 依托单位:
海外基金