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System-wide environmental perturbations transform understanding of relationships between high-dimensional data, exposures, and phenotypes

System-wide environmental perturbations transform understanding of relationships between high-dimensional data, exposures, and phenotypes
全系统的环境扰动改变了对高维数据、暴露和表型之间关系的理解
批准号：
343317
负责人：
Greenwood Celia M
金额：
$17.27万
依托单位：
Lady Davis Institute for Medical Research (Mtl)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-03-01 至 2019-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=343317&lang=en
关键词：
Data Integration Dimension Reduction Gene-Environment Interaction High Dimensional Modelling Penalization Prediction Modelling Statistical Methods In Genomics

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It is very challenging to develop reliable and understandable ways of predicting the risk of disease in individuals, based on high dimensional data such as genomic or imaging measures. This challenge is exacerbated when there are environmental exposures t
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