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Modular Design of Macromolecular Iron Chelator Structures for Chelation Therapy: Towards Effective Prevention of Primary and Transfusional Iron Overload

Modular Design of Macromolecular Iron Chelator Structures for Chelation Therapy: Towards Effective Prevention of Primary and Transfusional Iron Overload
用于螯合疗法的大分子铁螯合剂结构的模块化设计：有效预防原发性和输血性铁过载
批准号：
179252
负责人：
Kizhakkedathu Jayachandran N
金额：
$28.06万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-03-01 至 2012-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=179252&lang=en
关键词：
Controlled Polymerization Iron Chelation Polyethylene Glycol Polymer Based Iron Chelators Primary And Secondary Iron Overload Thalassemia

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英文摘要
Iron overload disease is primarily caused by the enhanced uptake of dietary iron (e.g. hemochromatosis) or by the repeated transfusion of red blood cells (RBCs) such as in the case of thalassemia and sickle cell anaemia disease. In the case of thalassemi
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