Graphite calorimeter probe for clinical radiation dosimetry

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This Idea-to-Innovation proposal builds on patent-pending probe calorimeter-based technology to take significant steps to bring to market a revolutionary new, self-calibrating radiation dosimeter system. This system is useful in clinical reference determination of delivered dose in the medical application of radiation to the treatment of cancer of radiation therapy units as well as in other applications involving the accurate measurement of ionizing radiation dose. The proposal aims to refine the design and manufacturing quality of the detector system, will have the system undergo third-party validation and will provide a foundation to establish and incorporate a start-up company, called Caldose. Caldose will be the first company to make available a self-calibrating dosimetry system for applications in radiation therapy clinics, dose calibration laboratories, as well as other irradiation facilities (food processing, nuclear medicine, radiobiology, medical sterilization, security services, etc.). Since current dose measurement systems rely on calibration coefficients obtained from a primary standards dose laboratory, their accurate use is limited to a particular set of standard conditions. Any use of these devices that deviates from these calibration conditions (e.g., a realistic patient setup) must be correctly accounted, which often leads to significant uncertainty on the measured dose. Our patent-pending technology is based on calorimetric concepts that have been established over the last 60 years by standards dosimetry labs, and offers the most direct means of measuring the delivered dose at the point of care.