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Immunogen design to elicit broadly neutralizing antibodies to influenza

Immunogen design to elicit broadly neutralizing antibodies to influenza
免疫原设计可引发广泛中和流感抗体
批准号：
183450
负责人：
Pantophlet Ralph A
金额：
$7.23万
依托单位：
Simon Fraser University (Burnaby, B.C.)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-03-01 至 2010-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=183450&lang=en
关键词：
Computational Protein Design Epitope Targeting Influenza Neutralizing Antibodies Vaccines Yeast Antibody Display

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中文摘要
翻译
流感疫苗刺激免疫系统产生抗体，防止病毒感染。虽然对与纳入疫苗的流感毒株相似的流感毒株非常有效，但这些抗体反应通常是不够的
英文摘要
Flu vaccines stimulate the immune system to produce antibodies that protect against viral infection. Although highly effective against influenza strains that are similar to those incorporated into the vaccine, these antibody responses are generally inadeq
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