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Mechanisms Coordinating Polo Kinase Activity and Localization in Cell Division

Mechanisms Coordinating Polo Kinase Activity and Localization in Cell Division
细胞分裂中 Polo 激酶活性和定位的协调机制
批准号：
355144
负责人：
Archambault Vincent
金额：
$66.04万
依托单位：
Institute for Research in Immunology and Cancer (Montreal, QC)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-10-01 至 2021-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=355144&lang=en
关键词：
Cancer Cell Division Chemogenomics Crispr Cytokinesis Drosophila Genetics Human Cells Mitosis Polo Kinase

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中文摘要
翻译
癌症是体内细胞的过度分裂。为了复制，细胞必须在有丝分裂期间分离两组相同的染色体并正确分裂。这一过程需要几个保守的蛋白质的协调活动，这些蛋白质是B
英文摘要
Cancer is the excessive division of cells in the body. To duplicate, cells must separate two identical sets of chromosomes during mitosis and divide correctly. This process requires the coordinated activities of several proteins that have been conserved b
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会议论文
Understanding Nuclear Envelope Reformation after Mitosis using Drosophila
Cell Cycle Control by the PP2A-B55 Module
Molecular Dissection of Mitotic Exit
Regulation of the Polo kinase by the Aurora and Greatwall kinases in Drosophila
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