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Molecular analysis of the Rac1/Cdc42 regulator CdGAP in development and breast cancer

Molecular analysis of the Rac1/Cdc42 regulator CdGAP in development and breast cancer
Rac1/Cdc42 调节剂 CdGAP 在发育和乳腺癌中的分子分析
批准号：
357762
负责人：
Lamarche-Vane Nathalie
金额：
$63.53万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-10-01 至 2021-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=357762&lang=en
关键词：
Breast Cancer Cell Migration Cytoskeleton Development Molecular Mechanisms Mouse Models Rho Gtpase Mechanisms Tgfb Signaling

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英文摘要
Breast cancer is the second cause of cancer-related deaths amongst women after lung cancer. The availability of a wide range of therapeutic approaches creates a need for the development of individualized medicine leading to more accurate and efficient tre
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Netrin-1 receptor "deleted in colorectal cancer" (DCC) signalosome in axonal development
Investigating the mechanisms underlying the Rac1/Cdc42 GTPase regulator CdGAP in breast cancer
Netrin-1 receptor "deleted in colorectal cancer" (DCC) signalosome in axonal development
Molecular mechanisms of CdGAP (Cdc42 GTPase-activating protein), a negative regulator of the oncogenic small GTPases Rac1 and Cdc42
  • 批准号：
    238425
  • 项目类别：
    Operating Grants
  • 资助金额：
    $49.48万
  • 财政年份：
    2011
  • 负责人：
    Lamarche-Vane Nathalie
  • 依托单位：
    McGill University
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