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Investigating the mechanisms underlying the Rac1/Cdc42 GTPase regulator CdGAP in breast cancer

Investigating the mechanisms underlying the Rac1/Cdc42 GTPase regulator CdGAP in breast cancer
研究乳腺癌中 Rac1/Cdc42 GTPase 调节剂 CdGAP 的潜在机制
批准号：
452222
负责人：
Lamarche-Vane Nathalie
金额：
$59.07万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
未结题
起止时间：
2021-09-01 至 2026-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=452222&lang=en
关键词：
Breast Cancer Cell Signaling Crispr/Cas9 Human Breast Cancer Cell Lines Mouse Models Rho Gtpases Rhogaps Tumor Angiogenesis Vascular Development

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Lay Abstract: Breast cancer is the second cause of cancer-related deaths amongst women after lung cancer. The availability of a wide range of therapeutic approaches creates a need for the development of individualized medicine leading to more accurate and
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Netrin-1 receptor "deleted in colorectal cancer" (DCC) signalosome in axonal development
Netrin-1 receptor "deleted in colorectal cancer" (DCC) signalosome in axonal development
Molecular analysis of the Rac1/Cdc42 regulator CdGAP in development and breast cancer
Molecular mechanisms of CdGAP (Cdc42 GTPase-activating protein), a negative regulator of the oncogenic small GTPases Rac1 and Cdc42
  • 批准号：
    238425
  • 项目类别：
    Operating Grants
  • 资助金额：
    $49.48万
  • 财政年份：
    2011
  • 负责人：
    Lamarche-Vane Nathalie
  • 依托单位：
    McGill University
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