Regulation of TrkA receptor trafficking and signaling by Calnuc

Calnuc 对 TrkA 受体运输和信号传导的调节

• 批准号: 181363
• 负责人: Lavoie Christine
• 金额: $ 45.02万
• 依托单位: Universit de Sherbrooke
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-03-01 至 2014-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=181363&lang=en
• 关键词: Cell Surface Receptors; Confocal Immunofluorescence; Endocytosis; Heterotrimeric G Protein; Intracellular Trafficking; Signal Transduction

Extracellular signaling molecules bind to specific receptors at the cell surface that will initiate a cascade of signal inside the cell and control a wide variety of biological responses such as proliferation, differentiation, migration and modulation of

细胞外信号分子与细胞表面的特定受体结合，将在细胞内启动信号级联，并控制各种生物反应，如增殖、分化、迁移和调节