Factors Affecting Memory Encoding and Retrieval: A Cognitive Neuroscience Approach
影响记忆编码和检索的因素:认知神经科学方法
基本信息
- 批准号:RGPIN-2015-05605
- 负责人:
- 金额:$ 2.4万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2016
- 资助国家:加拿大
- 起止时间:2016-01-01 至 2017-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Memory is the set of processes by which we encode and retain information from our environment, and subsequently access it to reconstruct past experiences and guide behaviour. My students and I use cognitive paradigms as well as functional magnetic neuroimaging to identify the processes required for successful memory, and to specify the neural basis of performance. The long-term goal of my research program is to specify factors affecting encoding and retrieval. Determining how these processes interact, at both the cognitive and neural levels, will highlight conditions and situations that help or hinder our ability to remember.
Prior research in my lab showed that memory is disrupted when another ongoing task competes for attention during encoding, or for similar materials during retrieval. Part 1 of this proposal will assess whether individual, and experimenter-induced, differences in representing information in memory influence successful retrieval, and will determine the generalizability of this finding to non-verbal materials. Part 2 will explore the hypothesis that recruiting additional context-specific brain regions during encoding produces more robust memory traces that can more readily and reliably be re-activated by various cues, protecting memories from negative effects of dual-tasking on memory. While success at retrieving information is one measure indexing memory status, the quality of one’s memory is another. Part 3 will consider how different encoding conditions influence the quality of the memory trace that is formed and subsequently retrieved. By comparing conditions, and populations (younger versus older adults), that allow for creation of more or less cohesive, contextually-bound memory traces, we can better specify the conditions and brain regions that support high-fidelity memories.
The convergence of work proposed here, at both the behavioural and neural levels, will refine a model of episodic memory initially developed in my lab using cognitive and neuroimaging methodologies. The proposed studies are important for several reasons. First, they highlight conditions and situations in which memory performance can be disrupted, providing insight into the limitations of human cognitive processing. Second, they identify a means for compensating for such interference effects. Finally, they determine encoding operations that can influence both the quantity and quality of what can be remembered.
All 3 facets of my research program build on significant progress made during the past funding cycle. My research program will serve to train students who will gain skills critical for research in cognitive neuroscience, highlighting ways to ameliorate memory despite deficits associated with normal aging, and with multi-tasking environments in young healthy adults which are ever more present in today’s fast-paced world.
记忆是一组过程,我们通过它来编码和保留来自我们环境的信息,并随后访问它来重建过去的经验和指导行为。我和我的学生使用认知范式和功能磁性神经成像来确定成功记忆所需的过程,并明确表现的神经基础。我的研究计划的长期目标是明确影响编码和检索的因素。确定这些过程如何在认知和神经层面上相互作用,将突出有助于或阻碍我们记忆能力的条件和情况。
我实验室之前的研究表明,当另一项正在进行的任务在编码过程中争夺注意力时,或者在提取过程中争夺类似的材料时,记忆就会中断。这项建议的第一部分将评估个体和实验者在记忆中表示信息的差异是否会影响成功的提取,并将确定这一发现对非语言材料的概括性。第二部分将探索这样一个假设,即在编码过程中招募额外的上下文特定脑区会产生更强大的记忆痕迹,这些痕迹可以更容易、更可靠地被各种线索重新激活,从而保护记忆免受双重任务对记忆的负面影响。检索信息的成功与否是衡量记忆状态的一个指标,而一个人的记忆质量则是另一个指标。第3部分将考虑不同的编码条件如何影响形成并随后检索的记忆轨迹的质量。通过比较条件和人群(年轻人和老年人),我们可以更好地确定支持高保真记忆的条件和大脑区域,这些条件和群体允许创建或多或少有凝聚力的、受背景限制的记忆痕迹。
这里提出的在行为和神经层面上的工作的融合,将完善我的实验室最初使用认知和神经成像方法开发的情景记忆模型。拟议中的研究之所以重要,有几个原因。首先,它们强调了记忆性能可能被破坏的条件和情况,提供了对人类认知处理的局限性的洞察。其次,他们确定了一种补偿这种干扰影响的方法。最后,他们决定了编码操作,这些操作可以影响所能记住的内容的数量和质量。
我的研究计划的所有三个方面都建立在上一个资助周期取得的重大进展的基础上。我的研究计划将帮助培训学生,他们将获得认知神经科学研究的关键技能,强调改善记忆的方法,尽管与正常衰老相关的缺陷,以及年轻健康成年人的多任务环境,在当今快节奏的世界中越来越多。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Fernandes, Myra其他文献
Improving associative memory in older adults with unitization
- DOI:
10.1080/13825585.2014.980216 - 发表时间:
2015-07-04 - 期刊:
- 影响因子:1.9
- 作者:
Ahmad, Fahad N.;Fernandes, Myra;Hockley, William E. - 通讯作者:
Hockley, William E.
Process-Specific Interference Effects During Recognition of Spatial Patterns and Words
- DOI:
10.1037/a0012870 - 发表时间:
2009-03-01 - 期刊:
- 影响因子:1.3
- 作者:
Fernandes, Myra;Guild, Emma - 通讯作者:
Guild, Emma
Functional specificity of the visual word form area: General activation for words and symbols but specific network activation for words
- DOI:
10.1016/j.bandl.2007.04.006 - 发表时间:
2008-02-01 - 期刊:
- 影响因子:2.5
- 作者:
Reinke, Karen;Fernandes, Myra;Grady, Cheryl L. - 通讯作者:
Grady, Cheryl L.
Are the memories of older adults positively biased?
- DOI:
10.1037/0882-7974.23.2.297 - 发表时间:
2008-06-01 - 期刊:
- 影响因子:3.7
- 作者:
Fernandes, Myra;Ross, Michael;Schryer, Emily - 通讯作者:
Schryer, Emily
Does It Matter Where We Meet? The Role of Emotional Context in Evaluative First Impressions
- DOI:
10.1037/a0019139 - 发表时间:
2010-06-01 - 期刊:
- 影响因子:1.3
- 作者:
Koji, Shahnaz;Fernandes, Myra - 通讯作者:
Fernandes, Myra
Fernandes, Myra的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Fernandes, Myra', 18)}}的其他基金
Factors influencing cognitive and neural representations contributing to memory
影响记忆的认知和神经表征的因素
- 批准号:
RGPIN-2020-03917 - 财政年份:2022
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Factors influencing cognitive and neural representations contributing to memory
影响记忆的认知和神经表征的因素
- 批准号:
RGPIN-2020-03917 - 财政年份:2021
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Factors influencing cognitive and neural representations contributing to memory
影响记忆的认知和神经表征的因素
- 批准号:
RGPIN-2020-03917 - 财政年份:2020
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Factors Affecting Memory Encoding and Retrieval: A Cognitive Neuroscience Approach
影响记忆编码和检索的因素:认知神经科学方法
- 批准号:
RGPIN-2015-05605 - 财政年份:2019
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Factors Affecting Memory Encoding and Retrieval: A Cognitive Neuroscience Approach
影响记忆编码和检索的因素:认知神经科学方法
- 批准号:
RGPIN-2015-05605 - 财政年份:2018
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Factors Affecting Memory Encoding and Retrieval: A Cognitive Neuroscience Approach
影响记忆编码和检索的因素:认知神经科学方法
- 批准号:
RGPIN-2015-05605 - 财政年份:2017
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Factors Affecting Memory Encoding and Retrieval: A Cognitive Neuroscience Approach
影响记忆编码和检索的因素:认知神经科学方法
- 批准号:
RGPIN-2015-05605 - 财政年份:2015
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Factors influencing memory encoding and retrieval
影响记忆编码和检索的因素
- 批准号:
311800-2010 - 财政年份:2014
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Factors influencing memory encoding and retrieval
影响记忆编码和检索的因素
- 批准号:
311800-2010 - 财政年份:2013
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Factors influencing memory encoding and retrieval
影响记忆编码和检索的因素
- 批准号:
311800-2010 - 财政年份:2012
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
相似海外基金
Factors Affecting Memory Encoding and Retrieval: A Cognitive Neuroscience Approach
影响记忆编码和检索的因素:认知神经科学方法
- 批准号:
RGPIN-2015-05605 - 财政年份:2019
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Factors Affecting Memory Encoding and Retrieval: A Cognitive Neuroscience Approach
影响记忆编码和检索的因素:认知神经科学方法
- 批准号:
RGPIN-2015-05605 - 财政年份:2018
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Factors Affecting Memory Encoding and Retrieval: A Cognitive Neuroscience Approach
影响记忆编码和检索的因素:认知神经科学方法
- 批准号:
RGPIN-2015-05605 - 财政年份:2017
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
A zebrafish screen to identify genes affecting working memory and age-related cognitive decline.
通过斑马鱼筛选来识别影响工作记忆和与年龄相关的认知能力下降的基因。
- 批准号:
BB/M007863/1 - 财政年份:2015
- 资助金额:
$ 2.4万 - 项目类别:
Research Grant
Identification of physiological factors affecting aging of working memory
影响工作记忆老化的生理因素识别
- 批准号:
15K17335 - 财政年份:2015
- 资助金额:
$ 2.4万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Factors Affecting Memory Encoding and Retrieval: A Cognitive Neuroscience Approach
影响记忆编码和检索的因素:认知神经科学方法
- 批准号:
RGPIN-2015-05605 - 财政年份:2015
- 资助金额:
$ 2.4万 - 项目类别:
Discovery Grants Program - Individual
Signals Affecting Homestasis and Tolerance in Memory T Cells
影响记忆 T 细胞稳态和耐受性的信号
- 批准号:
8468635 - 财政年份:2010
- 资助金额:
$ 2.4万 - 项目类别:
Signals Affecting Homestasis and Tolerance in Memory T Cells
影响记忆 T 细胞稳态和耐受性的信号
- 批准号:
8264562 - 财政年份:2010
- 资助金额:
$ 2.4万 - 项目类别:
Signals Affecting Homestasis and Tolerance in Memory T Cells
影响记忆 T 细胞稳态和耐受性的信号
- 批准号:
8660025 - 财政年份:2010
- 资助金额:
$ 2.4万 - 项目类别:
Signals Affecting Homestasis and Tolerance in Memory T Cells
影响记忆 T 细胞稳态和耐受性的信号
- 批准号:
7768851 - 财政年份:2010
- 资助金额:
$ 2.4万 - 项目类别: