Replacement of Life Sciences Institute Biomolecular Imager

nserc资助的UBC生命科学研究所（LSI）的3个系和2个学院的研究实验室率先使用生物分子成像仪进行了广泛的生物化学和分子应用。所有这些研究项目都需要敏感的方法来研究生物分子的相互作用，这是细胞中生化反应的基础。作为对放射性同位素和荧光/化学发光探针进行灵敏检测和定量的高度先进的工作机器，申请的GE Amersham台风5成像仪将允许申请人继续开发解决生物学基本问题的尖端方法。目前，LSI中现有的所有成像仪都无法正常工作且无法修复，因此迫切需要更换该成像仪。该仪器将允许nserc资助的研究项目继续开发新的方法，促进进一步的创新，并加强我们在生物科学方面的培训计划。该台风5号成像仪将支持申请人的持续卓越研究，这些申请人在过去六年中共获得超过1200万美元的研究和培训资金，发表了203篇出版物和3项专利（1项正在申请中），并培训了279名HQP。

NSERC-funded research labs from 3 departments and 2 faculties within the UBC Life Sciences Institute (LSI) have pioneered a broad variety of biochemical and molecular applications using biomolecular imagers. All of these research programs require sensitive approaches to study biomolecular interactions that are fundamental to biochemical reactions in the cell. As a highly advanced workhorse machine for the sensitive detection and quantitation of radioisotopes and fluorescent/chemiluminsescent probes, the requested GE Amersham Typhoon 5 imager will allow the applicants to continue developing cutting-edge approaches in addressing fundamental questions in biology. Currently, all existing imagers in the LSI are non-functional and irreparable, thus there is an urgent need to replace this imager. The instrument will allow the NSERC-funded research programs to continue developing new approaches, facilitate further innovation and enhance our training program in the biological sciences. This Typhoon 5 imager will support the continued research excellence of the applicants who over the last 6 years have collectively been awarded more that $12 million in funds for research and training, have produced 203 publications and 3 patents (1 pending), and trained 279 HQP.