K+ channels as key targets to favor alveolar epithelial integrity and function during the resolution of acute respiratory distress syndrome

K 通道是缓解急性呼吸窘迫综合征期间促进肺泡上皮完整性和功能的关键靶点

• 批准号: 366631
• 负责人: Brochiero Emmanuelle
• 金额: $ 7.29万
• 依托单位: Centre hospitalier de l'Universit de Montral (CHUM)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-11-01 至 2017-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=366631&lang=en
• 关键词: Acute Lung Injury/Acute Respiratory Distress Syndrome; Alveolar Epithelial Injury; Alveolar Epithelial Repair And Regeneration; Cellular And Animal Models; K+ Channels; Lung Edema; Lung Function; Lung Inflammation; Lung Physiopathology; Membrane Receptors

Acute respiratory distress syndrome (ARDS) is a devastating form of respiratory failure. Although the causes of ARDS may be multiple (infection, near drowning, physical trauma...), its initial phase commonly features severe injury of the epithelial cell l

急性呼吸窘迫综合征（ARDS）是一种毁灭性的呼吸衰竭。虽然ARDS的原因可能是多方面的（感染，溺水，身体创伤......），其初始阶段通常以上皮细胞严重损伤为特征，