Single-cell characterization of viral transcription- and translation-competent HIV reservoirs

具有转录和翻译能力的HIV病毒库的单细胞特征

• 批准号: 362369
• 负责人: Baxter Amy E
• 金额: $ 9.83万
• 依托单位: Centre hospitalier de l'Universit de Montral (CHUM)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-11-01 至 2019-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=362369&lang=en
• 关键词: Hiv Latency; Hiv Pathogenesis; Hiv Reservoirs; Latency-Reversing Agent; Memory Cd4 T Cells

Antiretroviral therapy (ART) represents a major leap forward in HIV treatment, but it is not a cure. As long as a patient takes their medication the virus is forced into hiding in cells, but it can reappear from these hiding places when ART is stopped. Th

抗逆转录病毒疗法（ART）代表了艾滋病毒治疗的一个重大飞跃，但它不是治愈方法。只要患者服药，病毒就被迫隐藏在细胞中，但当停止抗逆转录病毒治疗时，病毒就会从这些隐藏的地方重新出现。Th