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Role of lysosomal enzymes cathepsins B and D in neuronal vulnerability: potential implications in Alzheimer's disease pathology

Role of lysosomal enzymes cathepsins B and D in neuronal vulnerability: potential implications in Alzheimer's disease pathology
溶酶体酶组织蛋白酶 B 和 D 在神经元脆弱性中的作用:对阿尔茨海默病病理学的潜在影响
批准号:
369603
负责人:
Kar Satyabrata
金额:
$54.06万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01

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中文摘要
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英文摘要
Alzheimer's disease (AD) is a brain disease characterized by a gradual loss of memory, followed by deterioration of higher cognitive functions such as language, calculation and judgement. The pathological features associated with AD brain include the loss
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Role of activated astrocytes in APP metabolism and its functional implications in Alzheimer's disease pathology
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Role of beta-amyloid peptides in kainic acid-induced toxicity and its implications in temporal lobe epilepsy
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