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Native PLGA nanoparticles attenuate aggregation, phosphorylation and internalization of tau protein: potential implication in the treatment of Alzheimer's disease

Native PLGA nanoparticles attenuate aggregation, phosphorylation and internalization of tau protein: potential implication in the treatment of Alzheimer's disease
天然 PLGA 纳米粒子减弱 tau 蛋白的聚集、磷酸化和内化：在阿尔茨海默病治疗中的潜在意义
批准号：
487617
负责人：
Kar Satyabrata
金额：
$72.17万
依托单位：
University of Alberta
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2023
资助国家：
加拿大
项目状态：
未结题
起止时间：
2023-09-01 至 2028-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=487617&lang=en
关键词：
Alzheimer'S Disease Animal Models Of Alzheimer'S Disease Cognitive Deficits Induced Pluripotent Stem Cells Native Nanoparticles Neuroprotection Neurotoxicity Protein Aggregation Protein Disaggregation Tau Protein

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英文摘要
Alzheimer's disease (AD) is the most common cause of dementia affecting the elderly population in our society. People with AD suffer loss of memory and have trouble making decisions and using language. The disease is caused by two distinct clumps of prote
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