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Discovery and development of VISTA antagonists that restore antitumor immunity

Discovery and development of VISTA antagonists that restore antitumor immunity
恢复抗肿瘤免疫的 VISTA 拮抗剂的发现和开发
批准号:
370525
负责人:
Gariepy Jean
金额:
$62.7万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01

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中文摘要
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英文摘要
Immune checkpoint inhibitors (ICIs) represent a new class of typically antibody-based agents that restores the body's natural immune response directed at cancer cells. They do so by blocking signals, often sent by cancer cells to immune cells to dampen im
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Development of gastrointestinal track-targeted biologics to improve the treatment of inflammatory bowel disease (IBD)
Understanding and harnessing the therapeutic potential of VISTA: a PD-1-like negative immune checkpoint regulator
Design and in vivo delivery of novel anti-inflammatory agents
Targeted imaging and therapy of breast cancers using Tn antigen-specific DNA aptamers
  • 批准号:
    187558
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2009
  • 负责人:
    Gariepy Jean
  • 依托单位:
国内基金
海外基金
中国北方人群肺癌患者Cancer/Testis抗原表达谱绘制表位鉴定及功能性抗原特异性CTL制备研究
  • 批准号:
    81673007
  • 项目类别:
    面上项目
  • 资助金额:
    54.0万元
  • 批准年份:
    2016
  • 负责人:
    金时
  • 依托单位: