Neural responses to abiotic stress in insects

昆虫对非生物胁迫的神经反应

• 批准号: RGPIN-2017-04561
• 负责人: Robertson, Robert
• 金额: $ 5.03万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=630698
• 关键词: Neural; responses; abiotic; stress; insects

My research program is concerned with the impact of environmental factors, such as variable temperatures or oxygen availability, on the operation of nervous systems. This research is important for at least two reasons. From a purely biological perspective, the ability to cope with these environmental factors determines the geographical ranges of different species and understanding their physiological effects allows predictions about the ecological consequences of global climate change. From a biomedical perspective, the same factors are associated with human pathology such as fever, and oxygen deprivation resulting from a stroke. At a cellular level, neural mechanisms are remarkably similar in animals as diverse as locusts and humans, so my research with insects can generate hypotheses for others to test in mammalian models.

我的研究项目关注环境因素的影响，如温度变化或氧气供应，对神经系统的运作。这项研究之所以重要，至少有两个原因。从纯粹的生物学角度来看，科普这些环境因素的能力决定了不同物种的地理范围，了解它们的生理效应可以预测全球气候变化的生态后果。从生物医学的角度来看，同样的因素与人类病理学有关，如发烧和中风导致的缺氧。在细胞水平上，神经机制在蝗虫和人类等各种动物中非常相似，因此我对昆虫的研究可以为其他人在哺乳动物模型中进行测试提供假设。