Neuromuscular generation and control of force output in humans

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This research program has had a focus on determining key factors affecting the generation and control of muscle force in humans. By using an integrative systems level approach the primary objective is to continue to provide important information in this field that is applicable to both fundamental systems physiology and applied physiology. Core techniques permit a focus on the interrelationship between central neural drive and muscle contractile characteristics during the generation and voluntary control of movement. The human model offers several important opportunities for advancing knowledge in this area. Participants can comply with various requisite tasks that reflect normal activities that are dependent on effective muscle force generation and control in the integrated whole system. These include assessing the system at various levels from the motor cortex, spinal cord and peripheral nervous system to intrinsic properties of skeletal muscle including quantity (anatomy) and quality (physiology).