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Mechanisms of rod and cone disk membrane synthesis and quality control in normal and diseased retina.

Mechanisms of rod and cone disk membrane synthesis and quality control in normal and diseased retina.
正常和患病视网膜中视杆和视锥盘膜合成的机制和质量控制。
批准号：
371288
负责人：
Moritz Orson L
金额：
$54.34万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-09-01 至 2022-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=371288&lang=en
关键词：
Codon Bias Disk Membranes Er Quality Control Photoreceptors Protein Folding Retinal Degeneration Retinitis Pigmentosa Rhodopsin Rods And Cones Transgenic Animals

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中文摘要
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英文摘要
Retinal degenerative diseases are genetic disorders of the retina in which patients slowly lose their vision, resulting in blindness. Retinitis pigmentosa is a disorder causing death of rod photoreceptors, while other retinal degenerations affect both rod
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Mechanisms of cell death in inherited retinal degeneration caused by rhodopsin mutations
  • 批准号：
    371265
  • 项目类别：
    Operating Grants
  • 资助金额：
    $62.42万
  • 财政年份：
    2017
  • 负责人：
    Moritz Orson L
  • 依托单位：
    University of British Columbia
In-vivo analysis of mechanisms of cell death in inherited retinal degeneration