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Mechanisms of cell death in inherited retinal degeneration caused by rhodopsin mutations

Mechanisms of cell death in inherited retinal degeneration caused by rhodopsin mutations
视紫红质突变引起的遗传性视网膜变性的细胞死亡机制
批准号：
371265
负责人：
Moritz Orson L
金额：
$62.42万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-09-01 至 2022-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=371265&lang=en
关键词：
Confocal Microscopy Pharmacological Chaperones Photoreceptors Retina Retinal Degeneration Retinitis Pigmentosa Rhodopsin Rods And Cones Transgenics Xenopus Laevis

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中文摘要
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英文摘要
Retinitis pigmentosa (RP) is a devastating genetic disorder of the retina in which patients slowly lose their vision, resulting in blindness. The gene most commonly involved in RP is rhodopsin, which produces a protein that detects light. There are large
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Mechanisms of rod and cone disk membrane synthesis and quality control in normal and diseased retina.
  • 批准号：
    371288
  • 项目类别：
    Operating Grants
  • 资助金额：
    $54.34万
  • 财政年份：
    2017
  • 负责人：
    Moritz Orson L
  • 依托单位：
    University of British Columbia
In-vivo analysis of mechanisms of cell death in inherited retinal degeneration
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