The Role of Respiratory Chemoreflexes at Work, Rest and Play

呼吸化学反射在工作、休息和娱乐中的作用

• 批准号: RGPIN-2016-04915
• 负责人: Day, Trevor
• 金额: $ 2.26万
• 依托单位: Mount Royal University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=631550
• 关键词: Role; Respiratory; Chemoreflexes; Work; Rest

For decades, modern biological research has progressed down an increasingly microscopic scale, where understanding cellular, molecular and genetic mechanisms has been the dominant theme. Although important new discoveries toward understanding basic cellular mechanisms have resulted, this genomic perspective has been less predictive than anticipated on understanding body function, and surprisingly few medical advances have resulted. Integrative physiologists, who focus on understanding the functions of and relationships between organ systems, are now re-taking center stage in the pursuit of understanding biological function. One important biological function that still requires the research efforts of integrative physiologists is the control of breathing.

几十年来，现代生物学研究已经发展到越来越微观的规模，其中理解细胞，分子和遗传机制一直是主导主题。尽管在理解基本细胞机制方面有了重要的新发现，但这种基因组视角在理解身体功能方面的预测性低于预期，而且令人惊讶的是，几乎没有医学进展。综合生理学家，谁专注于了解器官系统的功能和之间的关系，现在重新采取中心舞台在追求理解生物功能。一个重要的生物学功能，仍然需要综合生理学家的研究工作是呼吸的控制。