Discovering mechanisms of pro-nociception: The role of spinal and supraspinal structures

发现促伤害感受机制：脊柱和脊柱上结构的作用

• 批准号: RGPIN-2016-05456
• 负责人: Kramer, John
• 金额: $ 2.62万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=631569
• 关键词: Discovering; mechanisms; pro; nociception; role

Although it is unpleasant, pain is crucial for all animals. Pain is a warning signal, to protect normal tissue from damage, and damaged tissue from further harm. The human experience of pain is incredibly variable: people respond differently to the same painful stimulus. While there are multiple reasons for this, recent evidence suggests that different people may actually be wired differently; that is, there are differences in how pain information is transmitted and encoded in the nervous system. The long-term goal of my research is to identify differences in pain processing.

尽管疼痛令人不快，但它对所有动物来说都是至关重要的。疼痛是一种警告信号，可以保护正常组织免受损伤，并保护受损组织免受进一步伤害。人类对疼痛的体验千差万别：人们对相同的疼痛刺激的反应不同。虽然造成这种情况的原因有多种，但最近的证据表明，不同的人实际上可能有不同的连接方式。也就是说，疼痛信息在神经系统中的传递和编码方式存在差异。我研究的长期目标是确定疼痛处理的差异。