Interfacing Mass Spectrometry with New Materials Developed for Fast Targeted Analysis

将质谱与新材料相结合以进行快速靶向分析

• 批准号: RGPIN-2015-06367
• 负责人: Bottaro, Christina
• 金额: $ 2.04万
• 依托单位: Memorial University of Newfoundland
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632565
• 关键词: Interfacing; Mass; Spectrometry; New; Materials

Widespread and varied sources of environmental contamination has led to public concern about threats to the availability of clean water, air and food. Such pressures increase demands to test broadly and frequently to assure health, safety and resource quality. This context motivates my ongoing research program to develop sensitive, fast, simple analytical approaches necessary for high throughput screening of aqueous samples, which are also suitable for use in wastewater assessment and treatment programs. The work proposed here has two interrelated research themes: A) development of selective materials, principally molecularly imprinted polymer (MIP) films, for uptake of target analytes from aqueous solutions, and B) development of desorption electrospray ionization-mass spectrometry (DESI-MS) methods for direct interrogation of analytes in the selective sorbents.

环境污染的来源广泛而多样，导致公众对清洁水、空气和食物的供应受到威胁表示关切。这种压力增加了广泛和频繁测试的需求，以确保健康，安全和资源质量。这种情况下，激励我正在进行的研究计划，以开发敏感，快速，简单的分析方法所需的高通量筛选的水样品，这也适用于废水评估和处理计划。这里提出的工作有两个相互关联的研究主题：A）选择性材料的发展，主要是分子印迹聚合物（MIP）膜，用于从水溶液中吸收目标分析物，和B）解吸电喷雾电离质谱（EST-MS）方法的发展直接询问的选择性吸附剂中的分析物。