Novel oxidative functionalizations using earth-abundant transition metals

选择性好氧氧化的发展对化学工业至关重要，因为分子氧丰富，并且通过其还原为水提供了可持续的能源。一组特别重要的氧化反应是将氧原子或氮原子直接一步转移到失活的有机底物上，这产生通常用作燃料、溶剂和润滑剂或用作精细化学品和药物合成中的结构单元的分子。此外，这些直接的原子转移避免了浪费的保护基团策略的中介作用。然而，大多数现有方法使用有毒金属离子或浪费的氧化剂，这对于按比例放大的应用是不期望的。

The development of selective aerobic oxidations is fundamentally important to the chemical industry due to the abundance of molecular oxygen and the sustainable source of energy provided by its reduction to water. A particularly important group of oxidation reactions is the direct, one-step transfer of an oxygen or nitrogen atom to an inactivated organic substrate, which generates molecules that are typically used as fuels, solvents and lubricants or as building blocks in the synthesis of fine chemicals and pharmaceuticals. Also, these direct atom transfers avoid the intermediacy of wasteful protecting-group strategies. However, most current methods employ toxic metal ions or wasteful oxidants, which is undesired for scaled-up applications.