Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
批准号:
RGPIN-2017-06683
负责人:
Wilds, Christopher
金额:
$3.28万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31
中文摘要
脱氧核糖核酸(DNA)和核糖核酸(RNA)是生命的核心分子。沃森和克里克在60多年前描述的DNA双螺旋结构的发现,继续引领着生物学和医学的无数进步。最近,这种优雅的结构及其特定相互作用的性质激发了科学家和工程师对核酸技术应用的研究。通过有机合成,核酸支架的修饰可以实现,从而使分子具有更大的功能,用于广泛的应用,可以改善我们的社会。
英文摘要
Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are the central molecules of life. The discovery of the double helix structure of DNA, described by Watson and Crick over 60 years ago, continues to lead to numerous advances in biology and medicine. More recently, this elegant structure and the nature of its specific interactions have inspired scientists and engineers to investigate technological applications for nucleic acids. Through organic synthesis, modification of the nucleic acid scaffold can be achieved leading to molecules with increased functionality for a broad range of applications that can improve our society.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
-
批准号:RGPIN-2017-06683
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2022
-
负责人:Wilds, Christopher
-
依托单位:
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
-
批准号:RGPIN-2017-06683
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2021
-
负责人:Wilds, Christopher
-
依托单位:
Urgent Replacement of a Biomolecular Imager For Bioorganic and Biological Chemistry Research
-
批准号:RTI-2021-00470
-
项目类别:Research Tools and Instruments
-
资助金额:$10.16万
-
财政年份:2020
-
负责人:Wilds, Christopher
-
依托单位:
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
-
批准号:RGPIN-2017-06683
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2020
-
负责人:Wilds, Christopher
-
依托单位:
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
-
批准号:RGPIN-2017-06683
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2019
-
负责人:Wilds, Christopher
-
依托单位:
Modified Nucleic Acid Structures to Interrogate Biochemical Processes and Design Principles of Responsive Nanodevices
-
批准号:RGPIN-2017-06683
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.28万
-
财政年份:2018
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and investigation of modified oligonucleotides as probes of DNA repair
-
批准号:299384-2011
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2016
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and investigation of modified oligonucleotides as probes of DNA repair
-
批准号:299384-2011
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2014
-
负责人:Wilds, Christopher
-
依托单位:
Biological Chemistry
-
批准号:1000213807-2009
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2013
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and investigation of modified oligonucleotides as probes of DNA repair
-
批准号:299384-2011
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2013
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and investigation of modified oligonucleotides as probes of DNA repair
-
批准号:299384-2011
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2012
-
负责人:Wilds, Christopher
-
依托单位:
Biological Chemistry
-
批准号:1000213807-2009
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2012
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and investigation of modified oligonucleotides as probes of DNA repair
-
批准号:299384-2011
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2011
-
负责人:Wilds, Christopher
-
依托单位:
Biological Chemistry
-
批准号:1000213807-2009
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2011
-
负责人:Wilds, Christopher
-
依托单位:
Biological Chemistry
-
批准号:1000213807-2009
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2010
-
负责人:Wilds, Christopher
-
依托单位:
Synthesis and characterization of chemically modified oligonucleotides as probes of DNA repair processes.
-
批准号:299384-2010
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2010
-
负责人:Wilds, Christopher
-
依托单位:
use of novel interstrand cross-linked DNA duplexes to investigate resistance to bifunctional alkylating chemotherapeutic agents
-
批准号:299384-2007
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2009
-
负责人:Wilds, Christopher
-
依托单位:
Biological Chemistry
-
批准号:1000213807-2009
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2009
-
负责人:Wilds, Christopher
-
依托单位:
Canada Research in Biological Chemistry
-
批准号:1000202062-2003
-
项目类别:Canada Research Chairs
-
资助金额:$7.29万
-
财政年份:2008
-
负责人:Wilds, Christopher
-
依托单位:
use of novel interstrand cross-linked DNA duplexes to investigate resistance to bifunctional alkylating chemotherapeutic agents
-
批准号:299384-2007
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2008
-
负责人:Wilds, Christopher
-
依托单位:
国内基金
海外基金
基于Zip Nucleic Acids引物对高度降解和低拷贝DNA检材的STR分型研究
-
批准号:81072511
-
项目类别:面上项目
-
资助金额:31.0万元
-
批准年份:2010
-
负责人:严江伟
-
依托单位:
肽核酸(Peptide Nucleic Acid - PNA)电化学生物传感器的研究
-
批准号:20703006
-
项目类别:青年科学基金项目
-
资助金额:20.0万元
-
批准年份:2007
-
负责人:李晓宏
-
依托单位: