Development of akinetic swept-source OCT for middle ear imaging

用于中耳成像的运动扫频 OCT 的开发

• 批准号: RGPIN-2015-06391
• 负责人: Adamson, Robert
• 金额: $ 2.55万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632938
• 关键词: Development; akinetic; swept; source; OCT

Optical coherence tomography (OCT) is an emerging optical imaging modality that can produce depth-resolved images of tissue. OCT is well-established in small-volume imaging applications in the retina and skin. My research is focused on its use for imaging the much larger volume of the middle ear. My proposal aims to develop techniques for fast real-time 2D imaging of the middle ear volume, Doppler OCT to enable functional imaging of the middle ear's response to sound and 3D imaging of the eardrum. Over the past five years my lab has built the first OCT system capable of obtaining images of the human middle ear at near real-time frame rates (3FPS). The current proposal will extend that work by moving from a time-domain OCT system to a new, akinetic swept-laser system that has become commercially available in the last year. This new laser offers many new capabilities that can improve middle ear imaging – true real time frame rates (>30FPS), a longer scanning range and exceptional phase stability for Doppler imaging and synthetic aperture imaging.

光学相干断层扫描（OCT）是一种新兴的光学成像方式，可以产生组织的深度分辨率图像。OCT在视网膜和皮肤的小体积成像应用中得到了很好的应用。我的研究重点是用它来成像中耳更大的体积。我的建议旨在开发中耳容量的快速实时2D成像技术，多普勒OCT技术，以实现中耳对声音反应的功能成像和鼓膜的3D成像。在过去的五年里，我的实验室已经建立了第一个能够以接近实时帧率（3FPS）获得人类中耳图像的OCT系统。目前的提案将通过从时域OCT系统转移到去年已商业化的新型动力学扫描激光系统来扩展这项工作。这种新型激光器提供了许多新功能，可以改善中耳成像-真正的实时帧率（bbb30fps），更长的扫描范围和多普勒成像和合成孔径成像的特殊相位稳定性。