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Sex-dependent systemic autoimmunity in a mouse model of Alzheimer's disease

Sex-dependent systemic autoimmunity in a mouse model of Alzheimer's disease
阿尔茨海默病小鼠模型中的性别依赖性系统自身免疫
批准号:
377925
负责人:
Fahnestock Margaret
金额:
$10.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-11-01 至 2019-11-01

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中文摘要
翻译
女性比男性更容易患阿尔茨海默病,但这种性别差异的原因尚不清楚。我们以前报道过,雄性阿尔茨海默病模型小鼠在记忆表现的同时,其免疫系统也发生了变化。
英文摘要
Women are more likely to develop Alzheimer's disease than men, but the reasons for this sex difference remain unclear. We previously reported that male Alzheimer model mice show changes in their immune system at the same time as their memory performance s
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会议论文
ProNGF and Mechanisms of Neurodegeneration in Aging and Alzheimer's Disease
  • 批准号:
    477901
  • 项目类别:
    Operating Grants
  • 资助金额:
    $90.28万
  • 财政年份:
    2023
  • 负责人:
    Fahnestock Margaret
  • 依托单位:
ProNGF and Neurodegeneration in Aging and Alzheimer's Disease
  • 批准号:
    381820
  • 项目类别:
    Operating Grants
  • 资助金额:
    $65.76万
  • 财政年份:
    2018
  • 负责人:
    Fahnestock Margaret
  • 依托单位:
Immunity, sex and genes in the etiology of Alzheimer's disease
  • 批准号:
    351772
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2016
  • 负责人:
    Fahnestock Margaret
  • 依托单位:
Microfluidic chambers for studies of aged basal forebrain cholinergic neurons
  • 批准号:
    228740
  • 项目类别:
    Operating Grants
  • 资助金额:
    $3.64万
  • 财政年份:
    2010
  • 负责人:
    Fahnestock Margaret
  • 依托单位:
海外基金