Identification of novel adaptor proteins required for localization of VPS13 to cellular membranes

鉴定将 VPS13 定位到细胞膜所需的新型接头蛋白

• 批准号: 386612
• 负责人: Dziurdzik Samantha K
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-12-01 至 2018-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=386612&lang=en
• 关键词: Chorea-Acanthocytosis; Cohen Syndrome; Early-Onset Parkinson'S Disease; Intracellular Trafficking; Membrane Contact Sites; Neurodegenerative Diseases; Protein Localization/Recruitment; Vacuolar Protein Sorting; Vps13; Yeast Model

Cells rely on a complex transportation system to regulate a multitude of functions within and between cellular compartments known as organelles. Disruptions in cellular trafficking have been implicated in a variety of neurological disorders. One method of

细胞依靠一个复杂的运输系统来调节细胞器内和细胞器之间的多种功能。细胞运输的中断与多种神经系统疾病有关。一种方法