Identification of membrane-targeting factors for neurodegeneration-associated proteins VPS13C and VPS13D

神经变性相关蛋白 VPS13C 和 VPS13D 膜靶向因子的鉴定

• 批准号: 417303
• 负责人: Dziurdzik Samantha K
• 金额: $ 7.65万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-11-01 至 2022-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=417303&lang=en
• 关键词: Amphipathic Helix; Genome-Wide Screen; Lipid Transport; Membrane Contact Sites; Membrane Curvature; Molecular Mechanisms Of Disease; Neurodegeneration; Parkinson'S Disease; Protein Localization; Spastic Ataxia

Inside each of our cells, we have a number of specialized compartments called organelles that perform different tasks. Recently we have learned that these compartments are not simply floating around in our cells but are in fact held together at places cal

在我们的每个细胞内，我们都有许多专门的隔室，称为细胞器，执行不同的任务。最近我们了解到，这些小隔间并不是简单地漂浮在我们的细胞中，事实上，它们是在细胞中的一个地方聚集在一起的。