Improved friction and wear performance in polymeric components of orthopaedic bearings.

改善骨科轴承聚合物部件的摩擦和磨损性能。

• 批准号: 5223-2013
• 负责人: Bryant, Tim
• 金额: $ 1.89万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=638433
• 关键词: Improved; friction; wear; performance; polymeric

Nearly 25,000 Canadians and 600,000 worldwide are implanted with an artificial knee each year. These devices are most often designed using specialized components made of metal (cobalt chrome) and plastic (ultrahigh molecular weight polyethylene). They are the treatment of choice for severe degenerative joint disease, and they are now being implanted in active patients, some as young as 45. As a result, there is an increased need to improve their durability, particularly with respect to wear in the plastic component. While there have been improvements in the design of polyethylene for use in hips, this has not been the case for highly stressed joints such as the knee. This project examines a novel way of treating the plastic material surface to reduce wear. It is thought that small indentations, or dimples, in the polyethylene surface will entrain joint fluid that will help lubricate the joint and also reduce the stress on the plastic itself. With reduced stress, reduced plastic wear should result. It is reasoned that human cartilage morphology, which has naturally occurring dimples less than 40 micrometers in diameter and 15 micrometers deep, could be used as a model for the surface texture. This geometry will be reproduced on polyethylene surfaces using specialized processing facilities at Queen's and tested to determine if this can reduce friction and wear in laboratory specimens. If successful, the texturing process will be evaluated on artificial joints in a wear simulator that reproduces loads and motion that occur in real life. The aim is to reduce the need to replace worn out artificial knees by improving their durability beyond the 15 years currently expected and provide a growing number of aging adults with a lifetime of activity well past what is now possible.

每年有近25，000名加拿大人和600，000名全世界的人植入人工膝关节。这些器械通常使用由金属（钴Chrome）和塑料（高分子量聚乙烯）制成的专用组件进行设计。它们是严重退行性关节疾病的首选治疗方法，现在正在植入活跃的患者中，其中一些人年仅45岁。因此，提高其耐久性的需求增加，特别是在塑料部件的磨损方面。虽然用于髋关节的聚乙烯设计有所改进，但对于高应力关节（如膝关节），情况并非如此。该项目研究了一种处理塑料材料表面以减少磨损的新方法。人们认为，聚乙烯表面的小凹痕或凹痕将夹带关节液，这将有助于润滑关节，并减少塑料本身的应力。随着应力的降低，应导致塑料磨损的减少。这是合理的，人类软骨形态，其中自然发生的酒窝直径小于40微米和15微米深，可以用作表面纹理的模型。将使用Queen's的专门加工设施在聚乙烯表面上复制这种几何形状，并进行测试，以确定这是否可以减少实验室样本中的摩擦和磨损。如果成功，将在磨损模拟器中对人工关节的纹理化过程进行评价，该模拟器再现真实的生活中发生的载荷和运动。其目的是通过提高人工膝关节的耐用性来减少更换磨损的人工膝关节的需求，使其超过目前预期的15年，并为越来越多的老年人提供超过现在可能的终身活动。