Analytical and Computational Tools for Long-Pulse Photoacoustics

长脉冲光声学的分析和计算工具

• 批准号: RGPIN-2016-04190
• 负责人: Baddour, Natalie
• 金额: $ 2.4万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=638757
• 关键词: Analytical; Computational; Tools; Long; Pulse

Photoacoustic signal generation is a technique which has demonstrated great potential for non-invasive medical tomography. With this technique, a short-pulse of laser energy is used on a sample. The absorbed energy produces a small temperature rise, which in turn induces a change in pressure inside the sample due to thermal expansion. This pressure acts as a source of ultrasound waves which can be detected by ultrasound detectors positioned outside the sample. Since there is a large difference between how blood and surrounding tissue absorb the light energy, this provides a way to look for anomalies in the tissue. This approach is thus suitable for imaging of the micro-vascular system, tumour detection or tissue characterization.

光声信号产生技术在非侵入性医学断层扫描中显示出巨大的潜力。使用这种技术，在样品上使用短脉冲激光能量。吸收的能量产生一个小的温升，这反过来又引起试样内部压力的变化，由于热膨胀。这种压力作为超声波的来源，可以被放置在样品外部的超声波探测器检测到。由于血液和周围组织吸收光能的方式存在很大差异，这为寻找组织中的异常提供了一种方法。因此，这种方法适用于微血管系统成像、肿瘤检测或组织表征。