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Investigating Proliferative Cell Nuclear Antigen (PCNA) Modification as a Source of R-loops and Genome Instability in Cancer

Investigating Proliferative Cell Nuclear Antigen (PCNA) Modification as a Source of R-loops and Genome Instability in Cancer
研究增殖细胞核抗原 (PCNA) 修饰作为癌症中 R 环和基因组不稳定性的来源
批准号:
386610
负责人:
Wells James P
金额:
$1.27万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-12-01 至 2018-12-01

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Cancer is a disease caused by mutations in normal DNA. High rates of mutations dubbed 'Genome instability' give rise to cancer, and can occur for many reasons. Environmental or endogenous damage to DNA can impair DNA replication. This replication stress c
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